Palmitoylation refers back to the modification of the cysteine thiols in proteins by fatty acids, mostly palmitic acid, by ‘thioester bond’ formation. In vivo, palmitoylation of proteins is catalyzed by palmitoyl acyltransferases (PATs or DHHC-PATs). Palmitoylation has just lately emerged as a vital post-translational modification in malarial parasites. The expression and exercise of palmitoyl transferases differ […]
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MicroRNA miR-19b-3p mediated G protein γ subunit 7 (GNG7) loss contributes lung adenocarcinoma progression through activating Hedgehog signaling
G protein γ subunit 7 (GNG7) is a subunit of heterotrimeric G protein. It has been demonstrated low expressed GNG7 in varied cancers. Nonetheless, the position of GNG7 in lung adenocarcinoma (LUAD) stays unclear. Within the current examine, GNG7 expression in LUAD tissues and cell strains was analyzed by RT-qPCR, western blot and immunohistochemical. Kaplan-Meier […]